En la enfermedad de Still, ¿cuál es la principal complicación potencialmente mortal que los clínicos deben vigilar? Si cree que sabe la respuesta, demuéstrelo en el quiz de RheumIQ de esta semana en https://t.co/KVK8J2iaFQ https://t.co/O62ZpIciWW

Mevalonate kinase deficiency (AKA hyper-IgD syndr-HIDS) is a rare autosomal recessive autoinflammatory dz of the MVK gene w/ exaggerated innate immunity & incr IL-1β production. Usually Dx in kids, milder forms of periodic fever syndrome have been seen in adults. https://t.co/0hAIz4JgY3

Machine learning predicts macrophage activation syndrome in adult Still’s disease – 312 AOSD – XGBoost model had 5 predictors: ferritin, splenomegaly, Plt#, cholesterol, & ESR (AUC 0.839, sensit 0.824, specificity 0.710. https://t.co/QrogaCYPCT https://t.co/Z6WgCnFTfx