NLRP3 Activation in Still's Disease
Adult-onset Still disease (AOSD) is usually regarded as an autoinflammatory disease, largely because of…
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New Criteria for the Cryopyrinopathies (CAPS)
The diagnosis of periodic fevers is unified by undiagnosed but recurrent fever. Unfortunately the…
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NIH Discovers Otulipenia – New Infantile Autoinflammatory Disorder
Researchers at the National Institutes of Health, led by Dr. Dan Kastner, have led…
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Canakinumab Yields Genetic and Disease Modifying Effects in TRAPS Patients
Tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is an autosomal-dominant autoinflammatory disease resulting…
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Epigenetic Changes to Inflammasome Found in Autoinflammatory Syndromes
Autoinflammatory syndromes manifest as periodic fevers in children, and are the result of monogenic,…
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New Classification Criteria for Macrophage Activation Syndrome
Systemic juvenile idiopathic arthritis (SoJIA) is one of the most common underlying etiologies to…
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RWCS 2016 – Periodic Fever and Macrophage Activation Syndrome + Pregnancy in IBD
Pregnancy and Immune Modulating Therapies Dr. Uma Mahadevan from UCSF discussed the use of…
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Should You Avoid Pneumococcal Vaccine in CAPS and Behcet's Patients
Althought EULAR currently recommends the pneumococcal vaccine be given to patients with inflammatory rheumatic diseases and…
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5 Mistakes When Diagnosing Adult-Onset Still’s Disease
Adult-onset Still’s disease is a rare systemic inflammatory disorder of unknown etiology and pathogenesis. AOSD…
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Real World Biologic Success in Systemic JIA
A retrospective review of 77 SoJIA patients revealed that 50-70% achieved inactive disease or remission when…
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