Still's Disease & Autoinflammatory Digest: August 2022

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Welcome to the new StillsNow monthly Newsletter!  StillsNow is an educational resource for physicians and patients, dedicated to Still’s Disease, Autoinflammatory and Febrile disorders. Be sure to subscribe to our monthly StillsNow Podcast on Apple or Android podcast platforms.

 

JAK Inhibitors in Difficult Still’s Disease

A small retrospective study suggests that patients with difficult to treat adult-onset Still’s disease (AOSD) or sytemic juvenile idiopathic arthritis (sJIA) may respond well to JAK inhibitor (JAKi) agents – presumable by blocking pro-inflammatory cytokines, notably IL-6 and IFN. Patients with sJIA or AOSD were gathered based on a national survey conducted in the departments of rheumatology,…

Not Still’s – Now What?

Your patient doesn’t meet criteria for Still’s disease (AOSD or sJIA), now what should you do or consider? What you do or consider next can be addressed according to the stage of current disease: A) Hospitalized Febrile Disease, or B) Outpatient “Still’s” Disease. Hospitalized patients: the diagnosis of Still’s disease is easier and more certain…

 
 

Rheumatic Causes for Fever of Unknown Origin

Fever of unknown origin (FUO) represents a diagnostic challenge to many physicians and while cancer and infectious causes need to be excluded, rheumatic disorders are amongst the most common causes of FUO. A recent metanalysisi of the medical literature from 2002 to 2021, included studies with ≥50 patients reporting on causes of FUO/IUO (inflammation of unknown…

Podcasts

QD Clinics – Still’s or Not – Part 2
Social Media Questions (7.29.2022)

Videos

StillsNow Innaugural Podcast July 2022 QD Clinic- Still's (or Not): Fever, Joint pain & Itchy Eyes

Resources

Best Drugs for Still’s Disease Labs & Diagnostic Tests for Still’s and Febrile Disorder

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